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eritropoietina

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Risorse esterne

identificativo Freebase
/m/01fwr3[1]
identificativo della Biblioteca del Congresso
sh85044756[2]

soggetto indicato come: Erythropoietin

identificativo RefSeq di una proteina
NP_000790[3]
identificativo YSO
38860[4]
Ensembl protein ID
ENSP00000252723[5]
identificativo Gran Enciclopèdia Catalana
eritropoetina
identificativo UniProt
P01588[6]
identificativo Gran Enciclopèdia Catalana (obsoleto)
0103932
identificativo Lex
epo
erythropoietin
identificativo UNII
64FS3BFH5W
identificativo NDL
00577035
identificativo WikiSkripta
15467
identificativo UK Parliament Thesaurus
9984

soggetto indicato come: Erythropoietin

identificativo PDB
1BUY[7]
1CN4[7]
1EER[7]
identificativo Microsoft Academic
2778534260
identificativo Thesaurus BNCF
73525
identificativo GND
4152964-9
identificativo NALT
28017
Great Russian Encyclopedia portal ID
eritropoetin-ea05f9
identificativo WorldNet 3.1 di un synset
14874504-n[8]
identificativo OpenAlex
C2778534260[9]
identificativo J9U della Biblioteca nazionale israeliana
987007553190405171[10]

sottoclasse di

proteina[6]

parte 'e

erythropoietin[11]
four-helical cytokine-like, core[11]
Erythropoietin/thrombopoeitin, conserved site, protein family[12]

trovato nella tassonomia de

Homo sapiens[6]

codificato da

eritropoietina[6]

funzione molecolare

funzione ormonale[13][14]

metodo di determinazione: IEA

protein kinase activator activity[15]

metodo di determinazione: IEA

legame dei farmaci alle proteine plasmatiche[16][17][18]

metodo di determinazione: IPI

erythropoietin receptor binding[19][20]

metodo di determinazione: IEA, IMP

cytokine activity[21]

metodo di determinazione: IDA

cytokine activity[22][23]

metodo di determinazione: IBA, IDA

erythropoietin receptor binding[24][14][23]

metodo di determinazione: IBA, IEA, IMP

protein kinase activator activity[25][23]

metodo di determinazione: IBA, IEA

componente cellulare

regione extracellulare[26][13][14]

metodo di determinazione: IEA, TAS

cell surface[27]

metodo di determinazione: IDA

cell body[25]

metodo di determinazione: IEA

spazio extracellulare[15][28]

metodo di determinazione: IDA, IEA

spazio extracellulare[25][27][23]

metodo di determinazione: IBA, IDA, IEA

processo biologico

erythrocyte maturation[13]

metodo di determinazione: IEA

negative regulation of cation channel activity[27]

metodo di determinazione: IDA

response to interleukin-1[25]

metodo di determinazione: IEA

response to hypoxia[15]

metodo di determinazione: IEA

negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress[27]

metodo di determinazione: IDA

response to nutrient[25]

metodo di determinazione: IEA

response to salt stress[25]

metodo di determinazione: IEA

negative regulation of erythrocyte apoptotic process[27]

metodo di determinazione: IDA

response to testosterone[25]

metodo di determinazione: IEA

regulation of transcription by RNA polymerase II[25]

metodo di determinazione: IEA

response to hyperoxia[25]

metodo di determinazione: IEA

positive regulation of Ras protein signal transduction[29]

metodo di determinazione: IDA

invecchiamento[25]

metodo di determinazione: IEA

negative regulation of apoptotic process[25]

metodo di determinazione: IEA

negative regulation of transcription by RNA polymerase II[30]

metodo di determinazione: IMP

response to electrical stimulus[25]

metodo di determinazione: IEA

circolazione del sangue[31]

metodo di determinazione: NAS

response to estrogen[25]

metodo di determinazione: IEA

cellular hyperosmotic response[27]

metodo di determinazione: IDA

positive regulation of transcription, DNA-templated[32]

metodo di determinazione: IDA

response to vitamin A[25]

metodo di determinazione: IEA

response to lipopolysaccharide[25]

metodo di determinazione: IEA

acute-phase response[25]

metodo di determinazione: IEA

peptidyl-serine phosphorylation[25]

metodo di determinazione: IEA

response to axon injury[25]

metodo di determinazione: IEA

hemoglobin biosynthetic process[15]

metodo di determinazione: IEA

positive regulation of neuron differentiation[25]

metodo di determinazione: IEA

positive regulation of cell population proliferation[15][29]

metodo di determinazione: IDA, IEA

regulation of transcription from RNA polymerase II promoter in response to hypoxia[26]

metodo di determinazione: TAS

positive regulation of ERK1 and ERK2 cascade[25]

metodo di determinazione: IEA

positive regulation of neuron projection development[25]

metodo di determinazione: IEA

negative regulation of calcium ion transport into cytosol[27]

metodo di determinazione: IDA

negative regulation of myeloid cell apoptotic process[25]

metodo di determinazione: IEA

activation of protein kinase activity[33]

metodo di determinazione: IEA

embryo implantation[25]

metodo di determinazione: IEA

trasduzione del segnale[31]

metodo di determinazione: NAS

positive regulation of activated T cell proliferation[25]

metodo di determinazione: IEA

positive regulation of protein kinase activity[25]

metodo di determinazione: IEA

negative regulation of neuron death[25]

metodo di determinazione: IEA

apoptosi[25]

metodo di determinazione: IEA

response to dexamethasone[25]

metodo di determinazione: IEA

proliferazione cellulare[24]

metodo di determinazione: IMP

erythrocyte differentiation[24][25][34]

metodo di determinazione: IDA, IEA, IMP

erythropoietin-mediated signaling pathway[19]

metodo di determinazione: IMP

positive regulation of tyrosine phosphorylation of STAT protein[32]

metodo di determinazione: IDA

regulation of signaling receptor activity[33]

metodo di determinazione: IEA

response to hypoxia[25][23]

metodo di determinazione: IBA, IEA

positive regulation of cell population proliferation[25][32][23]

metodo di determinazione: IBA, IDA, IEA

erythropoietin-mediated signaling pathway[24][23]

metodo di determinazione: IBA, IMP

hemoglobin biosynthetic process[25][23]

metodo di determinazione: IBA, IEA

positive regulation of Ras protein signal transduction[35][36]

metodo di determinazione: IBA, IDA

positive regulation of phosphatidylinositol 3-kinase signaling[26]

metodo di determinazione: TAS

positive regulation of Ras protein signal transduction[26][32][23]

metodo di determinazione: IBA, IDA, TAS

status giuridico medicina

boxed warning[37]

immagine Gene Atlas

corrisponde esattamente

http://purl.uniprot.org/uniprot/P01588[38]

è fatte 'e

azoto
carbonio
Erythropoietin/thrombopoeitin, conserved site[11]

categoria su Commons

Erythropoietin

Riferimento

  1. ↑ Freebase Data Dumps, 28 ott 2013
  2. ↑ Gemeinsame Normdatei
  3. ↑ NCBI Gene, 30 Maj 2020, 2056
  4. ↑ YSO-Wikidata mapping project, 19 Aùs 2024
  5. ↑ Ensembl Release 99, ENSP00000252723
  6. ↑ 6,0 6,1 6,2 6,3 UniProt, 13 Nuv 2019, P01588
  7. ↑ 7,0 7,1 7,2 P01588, 4 Aùs 2016, Lengua ngrese, UniProt
  8. ↑ GF WordNet
  9. ↑ OpenAlex, 26 Jen 2022, https://docs.openalex.org/download-snapshot/snapshot-data-format
  10. ↑ Biblioteca nazionale di Israele
  11. ↑ 11,0 11,1 11,2 InterPro Release 71.0, http://www.ebi.ac.uk/interpro/protein/P01588
  12. ↑ inferred from protein domain or family
  13. ↑ 13,0 13,1 13,2 GOA, 8 Abb 2019, P01588, UniProt, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01588, IEA
  14. ↑ 14,0 14,1 14,2 InterPro, 8 Abb 2019, GOA, IEA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01588
  15. ↑ 15,0 15,1 15,2 15,3 15,4 Ensembl, 27 Màr 2018, GOA, IEA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P01588&geneProductId=UniProtKB:P01588
  16. ↑ IntAct protein interaction database, 8 Abb 2019, Erythropoietin Stimulates Tumor Growth via EphB4., GOA, IPI, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01588
  17. ↑ IntAct protein interaction database, 8 Abb 2019, Efficiency of signalling through cytokine receptors depends critically on receptor orientation, GOA, IPI, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01588
  18. ↑ IntAct protein interaction database, 8 Abb 2019, LuTHy: a double-readout bioluminescence-based two-hybrid technology for quantitative mapping of protein-protein interactions in mammalian cells, GOA, IPI, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01588
  19. ↑ 19,0 19,1 Functional Selectivity in Cytokine Signaling Revealed Through a Pathogenic EPO Mutation, GOA, 27 Màr 2018, P01588, UniProt, http://www.ebi.ac.uk/QuickGO/annotations?protein=P01588&geneProductId=UniProtKB:P01588, IMP
  20. ↑ InterPro, 27 Màr 2018, GOA, IEA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P01588&geneProductId=UniProtKB:P01588
  21. ↑ British Heart Foundation, 27 Màr 2018, Functional Selectivity in Cytokine Signaling Revealed Through a Pathogenic EPO Mutation, GOA, IDA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P01588&geneProductId=UniProtKB:P01588
  22. ↑ British Heart Foundation, 8 Abb 2019, Functional Selectivity in Cytokine Signaling Revealed Through a Pathogenic EPO Mutation, GOA, IDA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01588
  23. ↑ 23,0 23,1 23,2 23,3 23,4 23,5 23,6 23,7 23,8 GO Central, 8 Abb 2019, Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium, GOA, IBA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01588
  24. ↑ 24,0 24,1 24,2 24,3 Functional Selectivity in Cytokine Signaling Revealed Through a Pathogenic EPO Mutation, GOA, 8 Abb 2019, P01588, UniProt, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01588, IMP
  25. ↑ 25,00 25,01 25,02 25,03 25,04 25,05 25,06 25,07 25,08 25,09 25,10 25,11 25,12 25,13 25,14 25,15 25,16 25,17 25,18 25,19 25,20 25,21 25,22 25,23 25,24 25,25 25,26 25,27 25,28 25,29 25,30 25,31 Ensembl, 8 Abb 2019, GOA, IEA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01588
  26. ↑ 26,0 26,1 26,2 26,3 Reactome, 8 Abb 2019, GOA, TAS, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01588
  27. ↑ 27,0 27,1 27,2 27,3 27,4 27,5 27,6 British Heart Foundation, 8 Abb 2019, Inhibition of Erythrocyte Cation Channels by Erythropoietin, GOA, IDA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01588
  28. ↑ British Heart Foundation, 27 Màr 2018, Inhibition of Erythrocyte Cation Channels by Erythropoietin, GOA, IDA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P01588&geneProductId=UniProtKB:P01588
  29. ↑ 29,0 29,1 British Heart Foundation, 27 Màr 2018, Insulin-like growth factor-I augments erythropoietin-induced proliferation through enhanced tyrosine phosphorylation of STAT5, GOA, IDA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P01588&geneProductId=UniProtKB:P01588
  30. ↑ British Heart Foundation, 8 Abb 2019, Hepcidin mRNA levels in mouse liver respond to inhibition of erythropoiesis, GOA, IMP, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01588
  31. ↑ 31,0 31,1 Proteome Inc., 8 Abb 2019, Isolation and characterization of genomic and cDNA clones of human erythropoietin, GOA, NAS, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01588
  32. ↑ 32,0 32,1 32,2 32,3 British Heart Foundation, 8 Abb 2019, Insulin-like growth factor-I augments erythropoietin-induced proliferation through enhanced tyrosine phosphorylation of STAT5, GOA, IDA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01588
  33. ↑ 33,0 33,1 Gene Ontology Consortium, 8 Abb 2019, GOA, IEA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01588
  34. ↑ British Heart Foundation, 8 Abb 2019, Disruption of ferroportin 1 regulation causes dynamic alterations in iron homeostasis and erythropoiesis in polycythaemia mice, GOA, IDA, http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01588
  35. ↑ British Heart Foundation, 10 set 2018, Insulin-like growth factor-I augments erythropoietin-induced proliferation through enhanced tyrosine phosphorylation of STAT5, GOA, IDA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P01588&geneProductId=UniProtKB:P01588
  36. ↑ GO Central, 10 set 2018, Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium, GOA, IBA, http://www.ebi.ac.uk/QuickGO/annotations?protein=P01588&geneProductId=UniProtKB:P01588
  37. ↑ FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links., https://nctr-crs.fda.gov/fdalabel/ui/spl-summaries/criteria/343802
  38. ↑ registro identifiers.org
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